Humana, BG Medicine partner on study - Business First of Louisville:

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More than 6,800 Humana customersa in Chicago and South Florida have enroller inthe trial, Louisville-based Humanq (NYSE: HUM) said in a news release. The studhy was open to men ages 55 to 80 and women ages 60to 80. Participantsz took a detailed surve and underwent various clinical including an advanced ultrasoundf scan of arteries in the neck anda CT-scab measurement of calcium deposits in the coronary They also provided blood “There is an increasing gap between what researc is teaching academic scientistws and the real world of clinicak medicine,” Carol McCall, vice president of research and development for Humana, said in the “With pioneering studies such as this one, BG Medicinw and Humana are employing a new approach to researchb — with the help of our health-plan members who volunteer to find solutiond that can provide better medical care for lower cos ts.
” Humana, which holds a minority equityh interest in Waltham, Mass.-based BG Medicine, is being paid for its services. More information about the study can be foundat .

Vanpooling service coming to region - St. Louis Business Journal:

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The two-year pilot is expected to beginj bythe fall. The program is a partnershipp of the Capital District Transportation the Capital DistrictTransportation Committee, the Downtown Alban Business Improvement District, the state Department of Transportation and the . is currentlyh recruiting businesses that might have employees coming from the same regionj who would be interested in participating inthe “The main thing is you have to have at leasr a minimum number of people to use the van,” Janack The way the program would work is one of the participantsw would also act as the driver.
The van would be assigned to a stay atthat person’s place of employment during the day and remain at the driver’sd home in the evening. The company providinfg the wheelsis Inc. out of Bordentown, N.J. VPSI had $62 million in revenue in 2008. VPSI was formed in 1977 and startexfor employees. Today, the company has 5,000 vans in operationn in more than 45 statesand 50,000 passengers. VPSI reportex “At this point, as soon as possible we hope to beginn rollingvans out,” said Jesse VPSI’s business development executive. The company expecta to have 20 vans in operation withintwo years.
“W expect to add one van or so each montbh through the life of the he said. For more information, call Mila Vega a CDTA plannerfat 437-6865.

Kendall

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million foreclosure lawsuit against the developer of theRivendelkl single-family home project in West Kendall. The Miami-based bank filer the foreclosure action on June 9agains Miami-based Crestview II, Marsol One LLC and managing membe r Marcial Solis, according to The complaint targets 28 unsold homes and home sitews in Rivendell, which is along Miller Drive (Southwesy 56th Street) between Southwest 167th Avenued and the Miccosukee Golf and Country After starting construction in 2004, Crestview II sold 103 homeds in Rivendell from 2005 through the most recent sale in Fort Lauderdale-based attorney Charles who represents TotalBank in its demand for $12.
w million on the outstanding mortgage, did not immediatel y return a call seeking comment. TotalBani reported having $86.4 million in late or unpaif loans, or nearly 6.5 percent of its total as of March 31. In March, filec a foreclosure action against Crestview II and Solis overa $2.1 millio mortgage.

Japan Budget Dependence on Debt to Rise to Record Next Year - BusinessWeek

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Mainichi Daily News

Japan Budget Dependence on Debt to Rise to Record Next Year BusinessWeek 24 (Bloomberg) -- Japan's budget for the year starting April showed the government more dependent than ever on bond sales to fund spending as Prime Minister Yoshihiko Noda struggles to tame the world's biggest public debt burden. ... Jap an Approves Main Budget for Next Fiscal Year W »

Report: D.C.-area home prices to keep falling - Washington Business Journal:

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California-based PMI (NYSE: PMI) reaches that conclusion in its Secondc Quarter 2009 Economic and Real EstateTrendes Report, and its U.S. Market Risk Index. The report says approximately 85 percentg ofthe nation's 381 metropolitan statisticakl areas (MSAs) are now facing increased risk of lowef home prices in 2011. Florida, California, Nevada and Arizonw continue to have the highest risk scorexs but an increased risk of lower future pricez is now spreading across all region s of the nation because of the significant increases in unemployment andforeclosure rates.
The Washington area which includesthe District, Northern Maryland and parts of West Virginiq — showed a 92 percent chance of lower prices. Baltimore has a 90 percent chance of homepricexs dropping, according to the report. "Rapidly risinb foreclosure and unemployment continuing declines in house and weakening consumer demand all workef to increase risk in the general and the housing market saidDavid Berson, PMI's chie economist and strategist.
"As a result of the continuefd weaknessin prices, and the relatively low level of interestt rates, improvements in affordability acros the nation's MSAs will continue to incentiviz e repeat and first-time homebuyers back into the market." The areae with the least chance of lowe prices, each with less than a 6 percen probability, include Cleveland; Columbus, Ohio; San Antonio; Houston; Dallas and Fort Texas, according to PMI. The risk of prices dropping runsat 99.9 percenty in Miami, Fort Lauderdale, West Palm Beach, Tampa and Jacksonville in Riverside, Los Angeles, Santa Ana, Sacramento and San Diegio in California; Las Vegas; Phoenix; Providence, and Detroit.

Boehringer Ingelheim Unveils Diabetes Pipeline

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June 6 /PRNewswire/ -- Boehringer Ingelheim Pharmaceuticals, Inc. today announcefd its pipeline of oral antidiabetic establishing itself in the type 2 diabetestherapeutid area. The Company is investigating compoundsd in Phase II and Phase III clinicalpdevelopment worldwide. New Phase II data resultas forlinagliptin (BI 1356), a dipeptidyll peptidase 4 (DPP-4) inhibitor and the Company's lead diabetesx compound, were presented today at the 69th Annuak American Diabetes Association (ADA) Scientificx Sessions in New Orleans. To view the multimedia assetsa associated withthis release, please clicj "Type 2 diabetes is a growing publidc health concern," said J.
Martin Carroll , Boehringe r Ingelheim USA Corporation presidenand CEO. "Our Company will draw from its knowledge and experience to help us delive on the much needed treatment options for patientsz who are living withthe disease. Boehringed Ingelheim is inspired to make a difference indiabetes care." Results from the Phase II study presented at ADA show that 1, 5 and 10 mg dosexs of linagliptin achieved clinicallyt relevant and statistically significant reductions in HbA1c, a measure of bloos sugar, when given as add-on therapy to type 2 diabetes patients inadequately controlled on metforminm (placebo-corrected changes from baseline; -0.40 percent for the 1 mg -0.
73 percent for the 5 mg and -0.67 percent for the 10 mg The most frequently reported adverse events in patients treatec with all doses of linagliptin comparex to placebo were (7.1 vs. 9.9 percent) diarrhea (2.5 vs. 4.2 and nausea (3.5 vs. 4.2 No cases of hypoglycemia were reporte d in patientsreceiving linagliptin.(1) "Many patientxs don't achieve adequate blood sugar contro with commonly used diabetes medicationsa like metformin. The significant reductiojn in HbA1c levels seen in this trial is encouragingy as it indicates linagliptin may have a potential role in the management of thisprevalent disease," said Dr.
Thor senior vice president, Medicine and Drug Regulatory Affairs, Boehringer Ingelheim Pharmaceuticals, Inc. "Type 2 diabetes is a progressivwe chronic condition that frequentlyrequires long-term treatment. A range of treatmentg options and combination regimens are needef so physicians can tailot therapy to the individualpatient needs. We are now awaiting results from additional ongoing studies which will furthetr assess the full potential of linagliptin for the treatment of type2 diabetes. DPP-4 inhibitors are a newer clasa of oral hypoglycemics that target the incretinhormones GLP-1 and GIP, which are believed to be involved with regulatinv blood sugar.
(2) Linagliptin is a compound discovered by Boehringer Ingelhein and is being developed as an oral once-dailyu tablet for the treatment of type 2 diabetes. The compound is currentlu being studied in five pivotal Phaswe III clinical trials including morethan 4,000 These trials are fully recruited and underwah globally and in many states across the U.S.(3) Boehringer Ingelheijm is also investigating sodium-dependent glucose co-transporter-2 inhibitors (SGLT-2 which are a new, emerging clasz of antidiabetic compounds that block tubular reabsorption of glucose in the Phase IIb clinical trials for this innovative approachh to diabetes treatment are There are currently no SGLT-2 inhibitors approved by the U.
S. Food and Drug Administrationb (FDA). The aim of the international, randomized, double-blind placebo-controlled study was to assess the efficacy and safetu profile of linagliptinas add-on therapy in patients with type 2 diabetes who were failiny to achieve glycemic control despite being treated with metformin.(1) The primary endpoint was the change in HbA1c from baseline to week Out of the 333 randomized patients, 268 patientzs received double-blind treatment with linagliptin (1 mg, 5 mg, n=66; 10 mg, n=66) or placebo.(1) An open-labeo arm with 65 patients on glimepiride was added for descriptive control.
(1) The additionb of linagliptin to metformin treatment for 12 weeks resulted in clinicallty relevant and statistically significant reductions in HbA1c and fastinb blood sugar or fasting plasma glucose levels (p-values of less than 0.05%):(1) -- Statisticallh significant reductions in mean HbA1c levels with linagliptib 5 mg and 10 mg comparedc with metformin alone (both p<0.001) were observed from week four though week 12.(1) -- In addition, all linaglipti doses showed significant reductions in FPG levels comparerd with metformin alone (placebo-corrected mean changes from baseline; -19.2 mg/dLo for 1 mg, -34.7 mg/d L for 5 mg, and -29.0 mg/dL for 10 mg).
(1) -- In the open-label comparator arm, the placebo-corrected mean change from baseline in HbA1xc was -0.90 percent.(1) -- More than 85% of the patienta receiving the 5mg and 10mg doses of linagliptinh demonstrated greater that or equal to 80% DPP-44 inhibition at trough at week -- HbA1c reductions of at leastr 0.5 percent were achieved in 44 percent to 53 percenf of patients on linagliptin, but only in 13 percent of the patientxs receiving metformin alone.(1) There are approximatelh 23.6(5) million Americans and 246 millionb people worldwide(6) with diabetes.
Type 2 diabetesx is the most common type of diabetesz accounting for morethan 90% of all diabetes cases in the developed Every ten seconds two people develop diabetes and one person dies from diabetes-related causews around the world.(6) Each year, more than 200,000 people in North America(6) and more than 3.8 milliojn people worldwide die from diabetes and its complications(6) -- a numbert which is expected to increase by more than 50 percenr over the next Diabetes is a chronic diseasee that occurs when the body does not properly produce or use the hormone, insulin.
(6) To addres this unmet need, Boehringer Ingelheim is committed to researchinbg and developing new compounds in this therapeuti area. Boehringer Ingelheim Pharmaceuticals, Inc. Boehringedr Ingelheim Pharmaceuticals, Inc., based in Ridgefield, CT, is the larges U.S. subsidiary of Boehringer IngelheimCorporatioj (Ridgefield, CT) and a member of the Boehringedr Ingelheim group of The Boehringer Ingelheim group is one of the world's 20 leadin pharmaceutical companies. Headquartered in Ingelheim, Germany, it operates globallyt with 138 affiliates in 47 countriews andapproximately 41,300 employees.
Since it was founde d in 1885, the family-owned compangy has been committedto researching, developing, manufacturingb and marketing novel products of high therapeutic value for humab and veterinary medicine. In 2008, Boehringe Ingelheim posted net sales ofUS $17 billion (11.6 billion euro) while spending approximately one-fifth of net saleas in its largest business segment, Prescriptiomn Medicines, on research and For more information, please visit . (1) DPP-4 inhibitor linagliptimn improves glycaemic control in type 2 diabetess patients when added to onogoingmetformij therapy. ADA, 05-09 June 2009, New Orleans, (2) Nathan DM et al.
Medicapl Management of Hyperglycemia in Type2 Diabetes: A Consensusa Algorithm for the Initiation and Adjustment of Diabetes Care 21:1-11, 2008. (3) Available at: . Accessed on: Apripl 30, 2009. (4) Jabbour SA, et al. Sodium glucose co-transported 2 inhibitors: blocking renal tubular reabsorption of glucose to improve glycaemic control in patientswith diabetes. Internationao Journal of Clinical Practice, July 2008. 62, 8, 1279-1284. (5) American Diabetes Association. 2007 National Diabetex Fact Sheet. (6) International Diabetes Diabetes Atlas. 3rd edn. International Diabetes Federation, 2006. (7) World Health Organization. Fact Sheet No. 312: What is Diabetes?? Available at: .
Accessed on: February 4, 2009. SOURC E Boehringer Ingelheim Pharmaceuticals, Inc.

Sprint's Decision to Stop Using Carrier IQ a Win for Privacy Advocates - PCWorld

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VentureBeat

Sprint's Decision to Stop Using Carrier IQ a Win for Privacy Advocates PCWorld By Christina DesMarais, PCWorld Dec 17, 2011 8:01 AM Sprint's decision to disable Carrier IQ software on its handsets and no longer collect data from the service is good news for people who have privacy concerns, but it also raises questions about how ... Sprint says it has stopped pulling Carrier IQ data from phones Los Angeles Times Sprint disables Carrier IQ software on its handsets Computerworld Here's how AT&T and Sprint are using Carrier IQ's data VentureBeat CBS News -CNN -Wired News  »

Think value-conscious, not just price-conscious, say tourism experts - New Mexico Business Weekly:

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Fortunately, it has a leg up in toutingf its value to travelers thankdsto AAA, which named Albuquerque the second most economical destinatiojn in the country in June 2008. Tourism officials have been incorporatinb that message in theirmarketing campaigns, said Taniaq Armenta, vice president of tourismk and communications with the . “Our spring campaig heavily toutsour affordability,” she said. The ACVB also will focusw on arts and cultural golf andoutdoor recreation. And for the first it will offer online cooperative advertisingfor members.
That’e a more affordable option for some Armenta said, because ACVB is doing the heav y lifting of marketing and advertising nationally to drive peoplew to the Web pages, so member s can get national exposurre through buying space at the ACVB has also been encouraging membersd to think differently and focus on the leisure market becaus e the meetings market is taking a biggefr hit right now, she said. Armenta, who is also presidenf of the , said there are also opportunities closed to home with the RailRunnerf Express. Art Bouffard, executivw director of the , said a numbeer of properties in Santa Fe have create packages around thecommuter train.
Prompting residents to travelo close to home is a focus of many marketingb efforts right now in the statetourisj industry. Some hoteliers are making an extraz effort to reach out to the Rich Verruni, managing director at in Santa Fe, has offered nonprofits special one-day packages for board meetingd or other events. The resort is also offering packages, such as free birthdag brunches anda three-course meal for with a bottle of wine, for $39.95. It’s also targeting its feedeer cities and former customers with offers arounxdkey dates. People are lookintg for anything that offers more valuew for theirtravel dollars, said Keithb Toler, executive director of the .
“What we are doing with our advertiseras is getting back to the basics and encouraging the industry to do the Toler said. “We’re encouraging them to make these types of offers and givinvg them space on our Web site topromotde them.” The Bureau is also shifting its marketing to focuzs on customers within 500 miles and emphasizing that Santw Fe offers something for every traveler’s Toler said. Some hoteliers caution, that discounting alone is a mistake. “I don’t believe in slashing rates. Discounting too much doesn’f create demand,” says Alfred Matter, general manager of the in Santa Fe.
“It takes two minutes to cut your ratesa and two years to getthem back.” Matter says the hotel has had success with its offet of a $199 room that includes a spa “I think consumers are much more value-conscious, not necessarily price-conscious,” he Jerry Westenhaver agrees. He’s the general manager of the . The Tamays has several packages, including a free spa treatmentt on your birthday if you bring a companiohn fora treatment. And Tamaya is gettin into and and already has abour450 “social stalkers,” he says.
“I think it’ the wave of the future,” he “In a recessionary period, you have to look at evert potential revenue source you can use to put yourselr out in thepublic arena.” The Santsa Ana Pueblo resort is also focusing on the locakl market and nearby travel markets. Tamaya got a nice boostt recently when named it one of the top valu hotels inthe country. For smaller propertiesx without a national it can be more challenging toreacbh customers. Kathy and Stevse Hiatt run thein Albuquerque’sw Old Town. They’re looking at additional packages theycan offer, she said, and tryinbg to lure locals for short getaways.

First green project in foreclosure - Silicon Valley / San Jose Business Journal:

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million construction mortgage. The 33,000-square-foot Vive Verde, also know as EcoCentre, is the first South Florida project seekin g Leadership in Energy and Environmental Design certification fromthe U.S. Green Building Councikl to face foreclosure. In an Romano said the extra cost ofthe building’s greenb features is not the reasohn it fell into foreclosure. “Thre fact that the building is a green building is not why the buildingb financially isin trouble,” Romani said.
“It has to do with a failure to properlt and adequately financially plan the building in the and I blame myself for Despitea cost-conscious office-leasing the concept of green office buildings is here to according to Christian Lee, vice chairman of in Miami, and Vive Verde’s foreclosure is just one entry on a long list of commercialo foreclosures that will happen regardless of whether a building is He noted that the more important factor for Romano’s building will be office demand in Lake “Building green adds to the cost [of a building], but in the long run, any greej building will be more attractive to an investord because it’s already green,” he said.
“Otherwise, new investorsw would be figuring in the cost to make it because all commercial buildings are going Rob Hink, a LEED-accredited consultan t with the Weston-based , agrees. “k don’t think this one foreclosurd on a green building is any commengt on the LEED system or green Ithink it’s just the he said. “I’m surprised because it’s a leased-up building.” He added that Romano’d large inner courtyard could have been downsizee to fit more rental space inthe building, and yet stillp have retained many of the environmentakl benefits. On May 26, Fort Lee, N.J.
-based filed the foreclosure actiojn against ViveVerde North, managinf member Romano and otherf parties associated with the project, accordintg to Palm Beach Countt Circuit Court records. The four-story at 1005 Lake in Lake Worth, was completerd in August. Its office spacd is about 70 percent leased, and it has two empty retail spaces, Romano said. The green features of the buildint work exactly ashe hoped, he A rooftop garden catches rainwater, while condensation is collectesd from the air conditioner for wateringb plants and ponds and flushing toilets. Grey water is recyclex in the water features ofthe atrium. The use of skylightss and windows cuts down onelectricity usage.
Many fixtures were made with recycledd materials. A sign outside advertises it asa “living Inside, goldfish swim through a pond and a statud of a Native American bathes in the sunlight in the Despite the energy and water savings, Vive Verde North has not made any paymentsd on the $6.9 million mortgage this year, said John an attorney with Carlton Fields in West Palm Beach who representss Meecorp in the lawsuit. “My client would like to get but ifthat doesn’t come to they are prepared to take title to the property and prepared to get paid that way, too,” Hart said. Vive Verdd North has a $4 million second mortgage with Williamsville, N.Y.
-based , whicb is named in Meecorp’s Romano said his company got behind on mortgage payments becausd it ran out of money and could not get the loan refinanceed by atraditional bank. “It is making me physicallty ill that thisis happening,” he “I will continue to work nighft and day to make this all work These days, I’m losing a lot of sleepl over it.” He said his plan for the building was flawed from the beginning because he wrots an incorrect financial plan. He said the construction for his firsg development project came in on budget and its utilitiesoperate efficiently.
Romano said the green features of Vive Verd e attractedsome tenants, although severapl of them would have signed leases in the building withougt them. He is confident the building will earn LEED but said that not opening with that designation has not hurt the Romano was aimingfor gold-level certification from the U.S. Greemn Building Council.

Bemis to buy Alcan Packaging Americas unit - Business First of Buffalo:

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billion. Neenah-based Bemis, a manufacturert of flexible packaging and pressure sensitive materialsfor food, consumerf products and other companies, said it is buying the Food Americas operationsz of Alcan from plc, an international miningt company. Bemis will acquire 23 Food Americaz flexible packaging facilities in theUnited States, Mexico, Brazil, Argentina, and New Zealand. The transaction include s Alcan facilitiesin Neenah, Menasha and Boscobel, accordingb to a Bemis spokeswoman. The 23 facilities producr flexible packaging for the food and beverages industries and employabout 4,600 workers. For the year ender Dec.
31, 2008, Chicago-based Alcan Packaging Food Americas recorded net salesof $1.5 billioh and adjusted earnings before expenses of approximately $166 million. "Botbh Bemis and Alcan Packaginghave strong, collaborative relationshipz with renowned food and consumer products customers," said Henry Theisen, Bemis president and CEO. "Wed each have a long history of dedicatiob to outstanding quality and manufacturing In poolingour resources, we will diversif our existing technologies and producr lines which will broaden our productf offering and augment our technical capabilities." The transaction will boostg Bemis’s annual net sales 40 percent to approximately $5.
3 with approximately 70 percent, up from 57 percent, of tota Bemis net sales coming from resilient food The addition of Alcan's employees will increase the company's globakl work force to more than 20,000 employees at 84 manufacturiny locations worldwide. Bemis expects to achieve more than $65 milliojn in annual cost savings by the end of thesecond year. Management intends to fund the purchase price with a combinationof $1 billioh in debt and $200 million in equity. and are actinv as financial advisers to Bemis forthis transaction, while LLP is actingf as primary legal adviser to Bemis.

SA to phase-out inefficient lighting by 2016 - Bizcommunity.com

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SA to phase-out inefficient lighting by 2016 Bizcommunity.com  »

Habana hails Williams - SuperSport.com

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BBC News

Habana hails Williams SuperSport.com Springbok great Bryan Habana has paid tribute to Shane Williams ahead of his fellow wing's final appearance for Wales and hopes his old rival can finish with a flourish against Australia. Saturday's match against the W »

Perry signs bill that includes $150 million for UTMB - Houston Business Journal:

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The university will use the fundd to build anew 200-bed hospital tower adjacent to the existing John Sealyg Hospital, restoring bed capacity to 550, as it was priotr to Hurricane Ike. In addition, tuition revenu e bonds of $5 million will go to at Galveston. HB 51 also establishex measures to enhance and maintain the quality ofthe state’z designated and emerging public research creates incentive programs and funding for higher educatiomn institutions, provides higher education fund allocations, and createes an interim committee to study the feasibility of trackinyg specialized technology research projects.
Of the 62 national researchb institutions inthe nation, three universitieds — , The and Texas A&M University — are in The Texas Higher Educatiojn Coordinating Board has designated seven institutions as emergin g research universities: the ; the University of Texas campusesw in Arlington, Dallas, El Paso and San Antonio; ; and the Universituy of North Texas. In HB 51 provides a performance incentive funding mechanism for all ofthe state’sz general academic institutions based on the average number of degreexs awarded annually and an increase in the average number of degrees awarded annually, with weighted consideratio for at-risk students and critical fields.

Centro's near-death experience - Sydney Morning Herald

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Sydney Morning Herald

Centro's near-death experience Sydney Morning Herald CENTRO Properties will now move to its next phase of being a debt-free, simply structured retail landlord, after its court battle with PricewaterhouseCoopers was withdrawn. After close to four years of battling to stay alive, Centro was given the green ... Court OKs Centro merger as refinancing f »